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Peptide Purification: A Lab Guide
Peptide Purification: A Lab Guide By: Clark Jones, PhD Synthetic peptides are indispensable tools in modern research, serving roles in drug discovery, structural biology, immunology, and biochemistry. However, crude peptides obtained directly after synthesis often contain a mixture of truncated sequences, deletion products, protecting groups, and other byproducts. To ensure accuracy in experiments, these peptides…
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What is a Lyophilized Peptide?
What is a Lyophilized Peptide? By: Dr. Anne Arnold Introduction Peptides are short chains of amino acids, usually two to fifty residues long, linked together by peptide bonds. They are larger and more complex than small molecules, yet smaller and simpler than proteins (Forbes & Krishnamurthy, 2025). This scale makes them useful in research because…
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Storage of Lyophilized Peptides
Storage of Lyophilized Peptides: A Lab Guide By: Clark Jones, PhD Lyophilized peptides—also known as freeze-dried peptides—are widely used in research due to their enhanced stability and extended shelf life. When properly stored, these peptides can remain chemically stable and biologically active for years. However, even small errors in storage conditions can lead to peptide…
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Reconstitution of Lyophilized Peptides
Reconstitution of Lyophilized Peptides: A Lab Guide By: Clark Jones, PhD Lyophilized peptides, stored in their dry, stable state, require careful reconstitution before they can be used in research applications. Whether working with synthetic peptides for binding assays, enzyme studies, or cellular models, correct handling during the rehydration process preserves peptide integrity and solubility. This…
